| Primary Identifier | MGI:1916782 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 74318 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables histone deacetylase regulator activity. Involved in positive regulation of gap junction assembly. Acts upstream of or within several processes, including lung alveolus development; positive regulation of skeletal muscle tissue regeneration; and trophectodermal cell differentiation. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; heart; trophectoderm; and urinary system. Orthologous to human HOPX (HOP homeobox). PHENOTYPE: Homozygous inactivation of this gene causes partial embryonic lethality due to severe developmental cardiac anomalies involving the myocardium, and leads to conduction defects in surviving adults. Mice homozygous for one null allele also exhibit impairedlung maturation leading to neonatal death. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
