|  Help  |  About  |  Contact Us

Protein Coding Gene : Acaca acetyl-Coenzyme A carboxylase alpha

Primary Identifier  MGI:108451 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  107476
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables acetyl-CoA carboxylase activity. Involved in acetyl-CoA metabolic process; fatty acid biosynthetic process; and protein homotetramerization. Acts upstream of or within several processes, including cellular response to prostaglandin E stimulus; lipid homeostasis; and tissue homeostasis. Located in cytosol. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Orthologous to human ACACA (acetyl-CoA carboxylase alpha).
PHENOTYPE: Homozygous null mice display embryonic lethality before embryo turning with growth arrest at the egg cylinder stage. [provided by MGI curators]
  • synonyms:
  • MGI:2443466,
  • MGD-MRK-37495,
  • gene model 738, (NCBI),
  • LOC327983,
  • Acc1,
  • Gm738,
  • RIKEN cDNA A530025K05 gene,
  • acetyl-CoA carboxylase,
  • A530025K05Rik,
  • acetyl-Coenzyme A carboxylase,
  • acetyl-Coenzyme A carboxylase alpha,
  • Acaca,
  • MGI:2685584,
  • Acac

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For