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Publication : Transcription factor NF 1 expression in involuting mammary gland.

First Author  Kane R Year  2000
Journal  Adv Exp Med Biol Volume  480
Pages  117-22 PubMed ID  10959417
Mgi Jnum  J:82305 Mgi Id  MGI:2652079
Doi  10.1007/0-306-46832-8_14 Citation  Kane R, et al. (2000) Transcription factor NF 1 expression in involuting mammary gland. Adv Exp Med Biol 480:117-22
abstractText  Transcripts of each of the four NF1 genes (NF1 A, B, C (CTF/NF1) and X) are expressed in both lactating and involuting mouse mammary gland but there is an indication that increased expression of an NF1 C (CTF/NF1) transcript accompanies early involution. The involution-associated 74 kD NF1 and the 114 kD lactation-associated NF1 are recognised by an anti-NF1 C-specific antibody that does not cross-react with other NF1 proteins. It is most likely that this lactation/involution switch in NF1 factors represents a change in expression of NF1 C (CTF/NF1) proteins.
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