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Allele : Polr3b<em5Tcp> polymerase (RNA) III (DNA directed) polypeptide B; endonuclease-mediated mutation 5, The Centre for Phenogenomics

Primary Identifier  MGI:6323011 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Polr3b
Strain of Origin  C57BL/6NCrl Is Recombinase  false
Is Wild Type  false
molecularNote  This allele from project TCPR0233 was generated at The Centre for Phenogenomics by injecting Cas9 ribonucleoprotein complexes with a single guide RNA with the spacer sequence TCATGTCCCTCAGACGGCAC resulting in two SNV changes C>T at Chr10:84632451 to disrupt PAM (within intron) and G>A at Chr10:84632459 which is predicted to result in a p.R103H change (GRCm38).
  • mutations:
  • Nucleotide substitutions
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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2 Publication categories

Trail: Allele