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Protein Coding Gene : Pald1 phosphatase domain containing, paladin 1

Primary Identifier  MGI:1351623 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  27355
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable protein tyrosine phosphatase activity. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Is expressed in several structures, including cardiovascular system; central nervous system; jaw; lung; and urinary system. Orthologous to human PALD1 (phosphatase domain containing paladin 1).
PHENOTYPE: Female, but not male, mice homozygous for a knock-out allele exhibit an emphysema-like phenotype associated with increased alveolar air spaces, impaired lung function, and increased lung endothelial cell apoptosis and proliferation. [provided by MGI curators]
  • synonyms:
  • X99384,
  • Pald,
  • cDNA sequence X99384,
  • phosphatase domain containing, paladin 1,
  • Pald1,
  • mKIAA1274,
  • paladin

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For