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Protein Domain : Rap guanine nucleotide exchange factor 2

Primary Identifier  IPR030739 Type  Family
Short Name  RapGEF2
description  RapGEF2 (CNrasGEF) is a Rap guanine nucleotide exchange factor that specifically activates Rap1 []. It is involved in embryonic hematopoiesis [], proper development of the midline commissures []and neuronal migration in the developing cerebral cortex []. It functions in the cAMP-induced Erk signalling pathway that leads to neuritogenesis []. It has a role in regulating cell proliferation and apoptosis [].

0 Child Features

1 Parent Features

5 Protein Domain Regions