|  Help  |  About  |  Contact Us

Comment :

Type  MGI:General Description  by 8 weeks of age, bones are soft and friable upon cutting multiple fractures evident in X-rays, with age- and bone-site related variation in the % of affected mice in young mice, most common fracture sites include the pelvis, olecranon process, and zygomatic arch, with frequencies of 82%, 80%, and 68% of mice, respectively the % of mice with fractured tarsals increases from 20% at 8 weeks to 58% at 20 weeks of age the % of mice with fractured scapulae and arthritic knees increases between 8 and 20 weeks of age (28% to 63% and 0% to 33% for scapulae and knees, respectively) significant number of mice with fractured tibial and fibular bones at 30 and 50 weeks of age