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Publication : A gene apparently determining the extent of sialylation of lysosomal alpha-mannosidase in mouse liver.

First Author  Dizik M Year  1977
Journal  Biochem Genet Volume  15
Issue  1-2 Pages  31-46
PubMed ID  849251 Mgi Jnum  J:5798
Mgi Id  MGI:54275 Doi  10.1007/BF00484546
Citation  Dizik M, et al. (1977) A gene apparently determining the extent of sialylation of lysosomal alpha-mannosidase in mouse liver. Biochem Genet 15(1-2):31-46
abstractText  Organ-specific electrophoretic heterogeneity of lysosomal alpha-mannosidase has been observed within individual strains of inbred mice. Polymorphism between C57BL/6J and CBA/J for liver lysosomal alpha-mannosidase is determined by a single genetic locus on chromosome 5 and appears to be the result of differences in sialylation of the lysosomal enzyme. Two different patterns of expression of development of the liver electrophoretic forms have been observed.
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