Primary Identifier | IPR024606 | Type | Family |
Short Name | DUF3827 |
description | The function of the proteins in this entry is not currently known, but one of the human proteins () has been implicated in pilocytic astrocytomas [, , ]. In the majority of cases of pilocytic astrocytomas a tandem duplication produces an in-frame fusion of the gene encoding this protein and the BRAF oncogene. The resulting fusion protein has constitutive BRAF kinase activity and is capable of transforming cells. |