| Primary Identifier | MGI:1856879 | Allele Type | Spontaneous |
| Gene | Ttc7 | Inheritance Mode | Recessive |
| Strain of Origin | A/J | Is Recombinase | false |
| Is Wild Type | false |
| description | The skin disorder is a progressive papulosquamous disease resembling some forms of human psoriasis. The cutaneous phenotype can be transferred with bone marrow grafts to Prkdcscid homozygous mice (J:14506). Full thickness skin grafts to Foxn1nu homozygotes retain the psoriasiform phenotype in this host lacking T cells (J:18002). Phenotypic Similarity to Human Syndrome: Psoriasis |
| molecularNote | An ETn early transposon insertion of 183 bp occurred in intron 1`4, 57 bp upstream of exon 15. |
