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Protein Coding Gene : Eif1a eukaryotic translation initiation factor 1A

Primary Identifier  MGI:95298 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  13664
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable ribosomal large subunit binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to act upstream of or within translation. Predicted to be part of eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; and multi-eIF complex. Predicted to be active in cytoplasm. Is expressed in several structures, including early conceptus; gonad; liver; lung; and spleen. Orthologous to human EIF1AX (eukaryotic translation initiation factor 1A X-linked).
PHENOTYPE: Female mice homozygous for a conditional ready, reporter allele are not viable, whereas males are viable and fertile. [provided by MGI curators]
  • synonyms:
  • eIF-1A,
  • MGD-MRK-33875,
  • MGD-MRK-9313,
  • Eftu,
  • eukaryotic translation initiation factor 1A,
  • C76390,
  • MGD-MRK-9310,
  • MGD-MRK-9330,
  • elongation factor Tu,
  • eukaryotic translation initiation factor 4C,
  • elongation factor 1 alpha,
  • Eif1a,
  • MGI:2147394,
  • Eif4c,
  • Ef1a,
  • expressed sequence C76390

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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6 Driver For