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Publication : Sequence of a novel carbonic anhydrase-related polypeptide and its exclusive presence in Purkinje cells.

First Author  Kato K Year  1990
Journal  FEBS Lett Volume  271
Issue  1-2 Pages  137-40
PubMed ID  2121526 Mgi Jnum  J:15409
Mgi Id  MGI:63532 Doi  10.1016/0014-5793(90)80390-5
Citation  Kato K (1990) Sequence of a novel carbonic anhydrase-related polypeptide and its exclusive presence in Purkinje cells. FEBS Lett 271(1-2):137-40
abstractText  I isolated a mouse cDNA clone encoding a novel polypeptide which has strong homology with carbonic anhydrase. Unlike the other carbonic anhydrases, it has an additional N-terminal domain with a glutamic acid stretch and an arginine substitutes one of the three histidine residues which bind zinc ion. In the central nervous system, carbonic anhydrase is known to be expressed only in glia cells, but this gene is expressed in neuron, but only in Purkinje cells.
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