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Allele : Rac1<tm1.1Nesh> Rac family small GTPase 1; targeted mutation 1.1, Norman E Sharpless

Primary Identifier  MGI:6781238 Allele Type  Targeted
Attribute String  Conditional ready Gene  Rac1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting construct inserted a floxed unit containing the wild type exons 2-6, three stop codons, and a FRT-site flanked Neomycin resistant cassette. A modified exon 2 with a point mutation in exon 2 generating the amino acid substitution of proline for serine at position 29 (P29S) was inserted after the loxP sites. Flp-mediated recombination removed the selection cassette.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • Rac1(P29S),
  • Rac1(P29S)
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele