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Protein Coding Gene : Slc4a8 solute carrier family 4 (anion exchanger), member 8

Primary Identifier  MGI:1928745 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  59033
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables sodium,bicarbonate:chloride antiporter activity. Involved in regulation of synaptic vesicle exocytosis. Acts upstream of or within positive regulation of synaptic vesicle exocytosis and regulation of intracellular pH. Located in several cellular components, including basolateral plasma membrane; neuronal cell body membrane; and presynaptic membrane. Is active in glutamatergic synapse. Is expressed in several structures, including adrenal gland; alimentary system; genitourinary system; nervous system; and sensory organ. Orthologous to human SLC4A8 (solute carrier family 4 member 8).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal sodium and chloride ion excretion. [provided by MGI curators]
  • synonyms:
  • Slc4a8,
  • solute carrier family 4 (anion exchanger), member 8,
  • MGI:2146219,
  • KNBC-3,
  • expressed sequence AW493845,
  • sodium bicarbonate cotransporter isoform 3 kNBC-3,
  • AW493845,
  • NDCBE

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For