| Primary Identifier | MGI:7431460 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Fscn3 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CAGCAATTAGCACAGCCAAG and GGAGAAAGTATGTCTAGGCA, which resulted in a 263 bp deletion beginning at Chromosome 6 position 28,431,420 bp and ending after 28431682 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000191890 (exon 3) and 144 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 280 and early truncation 8 amino acids later. |
