Primary Identifier | MGI:1096389 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 18191 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables calcium channel regulator activity. Involved in modulation of chemical synaptic transmission; neurotransmitter receptor localization to postsynaptic specialization membrane; and postsynaptic density assembly. Acts upstream of or within neurotransmitter secretion and synapse assembly. Part of protein-containing complex. Is active in GABA-ergic synapse; glutamatergic synapse; and presynaptic active zone membrane. Is expressed in several structures, including inner ear; nervous system; neural retina; urinary system; and vibrissa. Orthologous to human NRXN3 (neurexin 3). PHENOTYPE: Twenty percent of mice homozygous for a knock-out allele die postnatally prior to 20 days of age. [provided by MGI curators] |