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Protein Coding Gene : Nrxn3 neurexin III

Primary Identifier  MGI:1096389 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  18191
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables calcium channel regulator activity. Involved in modulation of chemical synaptic transmission; neurotransmitter receptor localization to postsynaptic specialization membrane; and postsynaptic density assembly. Acts upstream of or within neurotransmitter secretion and synapse assembly. Part of protein-containing complex. Is active in GABA-ergic synapse; glutamatergic synapse; and presynaptic active zone membrane. Is expressed in several structures, including inner ear; nervous system; neural retina; urinary system; and vibrissa. Orthologous to human NRXN3 (neurexin 3).
PHENOTYPE: Twenty percent of mice homozygous for a knock-out allele die postnatally prior to 20 days of age. [provided by MGI curators]
  • synonyms:
  • Nrxn3,
  • 4933401A11Rik,
  • MGI:1924757,
  • MGI:1921683,
  • 9330112C09Rik,
  • D12Bwg0831e,
  • DNA segment, Chr 12, Brigham & Women's Genetics 0831 expressed,
  • neurexin III beta,
  • RIKEN cDNA 9330112C09 gene,
  • neurexin III alpha,
  • RIKEN cDNA 4933401A11 gene,
  • MGI:106346,
  • MGD-MRK-34038,
  • neurexin III

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For