First Author | Fujita A | Year | 2000 |
Journal | Biochem Biophys Res Commun | Volume | 269 |
Issue | 1 | Pages | 1-6 |
PubMed ID | 10694467 | Mgi Jnum | J:61038 |
Mgi Id | MGI:1354256 | Doi | 10.1006/bbrc.1999.1893 |
Citation | Fujita A, et al. (2000) SAP family proteins. Biochem Biophys Res Commun 269(1):1-6 |
abstractText | Thus far, five members including Dlg, SAP97/hDlg, SAP90/PSD-95, SAP102, and PSD-93/chapsyn110 which belong to SAP family have been identified. Recent studies have revealed that these proteins play important roles in the localization and function of glutamate receptors and K(+) channels. Although most of them have been reported to be localized to the synapse, only one member, SAP97, is expressed also in the epithelial cells. In this review, we have summarized structural characters of SAP family proteins and discuss their functions in neurons and epithelial cells. Copyright 2000 Academic Press. |