Primary Identifier | MGI:6159873 | Allele Type | Targeted |
Gene | Nphp3 | Transmission | Germline |
Strain of Origin | C57BL/6NJcl | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A GGC -> GCC (G2A) mutation was inserted in exon 1 and a floxed neo cassette was inserted in intron 1 via homologous recombination. Cre mediated recombination removed the neo cassette. The mutation disrupts targeting of the protein to the cilia. |