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Allele : Tg(tetO-ptxA)1Conk transgene insertion 1, Bruce R Conklin
Primary Identifier  MGI:4455185 Allele Type  Transgenic
Attribute String  Inducible, Inserted expressed sequence Gene  Tg(tetO-ptxA)1Conk
Strain of Origin  FVB/N Induced With  doxycycline/tetracycline
Is Recombinase  false Is Wild Type  false
molecularNote  This transgene contains the tetracycline transactivator responsive element (TRE) driving expression, from a minimal promoter, of the catalytic S1 subunit of pertussis toxin, encoded by ptxA. This permits tTA (tet-off) or rtTA (tet-on) to induce expression of PTX-S1, which blocks signaling via the pertussis toxin-sensitive G proteins (Gi and Go).
  • mutations:
  • Insertion
  • synonyms:
  • tetO-PTX,
  • tetO-PTX,
  • Tg(tetO-PTX)1Conk,
  • Tg(tetO-PTX)1Conk
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

0 Driven By

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Trail: Allele




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