| Type | MGI:General | Description | conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) is impaired in maternal zygotes: the 5mC level remains high while the 5hmC level remains low in the male pronucleus; however, injection of Mettl23 mRNA into oocytes restores the 5mC to 5hmC conversion in maternal zygotes |
