Primary Identifier | MGI:2384811 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 210973 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Acts upstream of or within with a positive effect on several processes, including glucose metabolic process; phosphatidylinositol 3-kinase/protein kinase B signal transduction; and response to insulin. Orthologous to human KBTBD2 (kelch repeat and BTB domain containing 2). PHENOTYPE: Mice homozygous for a knock-out allele or mutation exhibit diabetes, lipodystrophy, and hepatic steatosis. [provided by MGI curators] |