| First Author | Sentman CL | Year | 1989 |
| Journal | Hybridoma | Volume | 8 |
| Issue | 6 | Pages | 605-14 |
| PubMed ID | 2613267 | Mgi Jnum | J:23866 |
| Mgi Id | MGI:71673 | Doi | 10.1089/hyb.1989.8.605 |
| Citation | Sentman CL, et al. (1989) Pan natural killer cell monoclonal antibodies and their relationship to the NK1.1 antigen. Hybridoma 8(6):605-14 |
| abstractText | The study of natural killer (NK) has been difficult because they account for a small percentage of peripheral blood and splenic lymphocytes and the paucity of NK specific antigens that have been identified. We have isolated pure populations of C57BL/6 (H-2b) NK cells using the IgG2b monoclonal antibody PK136 (anti-NK1.1). These NK1.1+ cells were used to immunize 129/J (H-2b) mice, and in this report, we describe three new NK specific monoclonal antibodies (SW3A4(IgM), SW4B12(IgG1), and SW2B4(IgG2b] and their relationship to the known murine NK antigen NK1.1. We have further characterized the NK1.1 antigen as a 39 kd molecule which is coded for by a gene which appears to map to chromosome 6. |
