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Protein Coding Gene : Ess2 ess-2 splicing factor

Primary Identifier  MGI:107854 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  27886
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Involved in nervous system development. Located in nucleus. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; face; and limb bud. Orthologous to human ESS2 (ess-2 splicing factor homolog).
PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality. Mice homozygous for a conditional allele activated in T cells exhibit reduced peripheral naive T cells and failure to maintain survival in response to IL-7. [provided by MGI curators]
  • synonyms:
  • ess-2 splicing factor,
  • expressed sequence AI462402,
  • expressed sequence 2 embryonic lethal,
  • AI462402,
  • Dgsi,
  • MGD-MRK-36431,
  • Dgcr14,
  • DiGeorge syndrome gene i,
  • DiGeorge syndrome critical region gene 14,
  • DNA segment, Chr 16, human D22S1269E, expressed,
  • Es2el,
  • MGI:892008,
  • MGI:2146439,
  • ES2,
  • Ess2,
  • D16H22S1269E

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Genome

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13 Involved In Mutations

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

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Proteins

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