| Type | MGI:General | Description | in the chronic model of colitis with low doses of DSS, mice exhibit increased number of larger tumors in the colon, accompanied by the development of marked leukocyte infiltration, extensive hyperplastic and neoplastic foci especially near the mucosal surface in the colon in AOM/DSS-induced tumorigenesis, mice show more weight loss, shortened colon length, and increased number of larger tumors in the colon AOM/DSS-induced mice show more rapidly progressing colorectal cancer because of more numerous invasive glands in the distal colons that invade deeper into the mucosal wall |
