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Allele : Adamts13<tm1Myta> ADAM metallopeptidase with thrombospondin type 1 motif 13; targeted mutation 1, Toshiyuki Miyata

Primary Identifier  MGI:3763820 Allele Type  Targeted
Attribute String  Null/knockout Gene  Adamts13
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
description  ES cell line = "R-CMTI-1A" (J:125786)
molecularNote  The exons 3-6 that encode the catalytic domain of the protein were replaced with a neomycin resistance cassette. Elimination of gene expression in homozygotes was confirmed by quantitative RT PCR on liver RNA and by the lack of enzymatic activity of the gene product in plasma.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Adamts13<->,
  • Adamts13<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele