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Publication : Isolation and bacterial expression of a murine alpha leukocyte interferon gene.

First Author  Daugherty B Year  1984
Journal  J Interferon Res Volume  4
Issue  4 Pages  635-43
PubMed ID  6094686 Mgi Jnum  J:17550
Mgi Id  MGI:65587 Doi  10.1089/jir.1984.4.635
Citation  Daugherty B, et al. (1984) Isolation and bacterial expression of a murine alpha leukocyte interferon gene. J Interferon Res 4(4):635-43
abstractText  A murine alpha interferon gene (MuIFN-alpha A) was isolated from a murine genomic DNA library in phage lambda. The gene was cloned and its sequence determined. It was expressed in Escherichia coli under the control of the trp promoter/operator which resulted in antiviral activity on mouse L-cells. MuIFN-alpha A exhibits 60% homology to HuIFN-alpha A at the amino acid level.
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