First Author | Daugherty B | Year | 1984 |
Journal | J Interferon Res | Volume | 4 |
Issue | 4 | Pages | 635-43 |
PubMed ID | 6094686 | Mgi Jnum | J:17550 |
Mgi Id | MGI:65587 | Doi | 10.1089/jir.1984.4.635 |
Citation | Daugherty B, et al. (1984) Isolation and bacterial expression of a murine alpha leukocyte interferon gene. J Interferon Res 4(4):635-43 |
abstractText | A murine alpha interferon gene (MuIFN-alpha A) was isolated from a murine genomic DNA library in phage lambda. The gene was cloned and its sequence determined. It was expressed in Escherichia coli under the control of the trp promoter/operator which resulted in antiviral activity on mouse L-cells. MuIFN-alpha A exhibits 60% homology to HuIFN-alpha A at the amino acid level. |