Primary Identifier | MGI:3761627 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Serpinb1a |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was introduced into intron 6 and a floxed Hyg-TK selection cassette into intron 7. Exon 7 and the selection cassette were removed by transient Cre expression, leaving a single loxP site behind. Western blot analysis on bone marrow neutrophils from homozygote mice indicated there was no expression of the wild-type allele. |