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Publication : Sequence of an epidermal growth factor-binding protein.

First Author  Lundgren S Year  1984
Journal  J Biol Chem Volume  259
Issue  12 Pages  7780-4
PubMed ID  6330081 Mgi Jnum  J:32315
Mgi Id  MGI:79815 Doi  10.1016/s0021-9258(17)42861-4
Citation  Lundgren S, et al. (1984) Sequence of an epidermal growth factor-binding protein. J Biol Chem 259(12):7780-4
abstractText  A cDNA clone has been isolated that corresponds to the entire translated region of the mRNA coding for the epidermal growth factor-binding protein type B. The complete nucleotide sequence and the predicted amino acid sequence of the protein were elucidated. The protein sequence was compared to some related serine proteases. This comparison supports the notion that several serine proteases suggested to be involved in the processing of precursors to polypeptide hormones and growth factors are closely related to each other. It appears that these proteases are descendants of a common ancestral gene and thus form a distinct subfamily among the serine proteases.
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