| Type | MGI:General | Description | in a model of active systemic anaphylaxis, where initial OVA immunization is followed by i.v. injection with 10 mg OVA, homozygotes show a significantly higher and faster death rate, with 68% vs only 27% of wild-type dying after systemic antigen challenge, and mean survival times of 26 ± 8 min and 45 ± 9 min, respectively |
