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Protein Domain : Protein phosphatase 1 regulatory subunit 17

Primary Identifier  IPR033242 Type  Family
Short Name  PPP1R17
description  Protein phosphatase 1 regulatory subunit 17, also known as G-substrate, is a substrate for cGMP-dependent protein kinase (PKG) and is primarily located in cerebellar Purkinje cells []. G-substrate phosphorylated by PKG inhibits the catalytic subunit of both protein phosphatase-1 and -2A [, ]. G-substrate regulates cerebellum-dependent long-term memory and it acts as a neuroprotectant in the ventral tegmental area and retina [].

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1 Protein Domain Regions