| Primary Identifier | MGI:88004 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 11702 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable adenosylmethionine decarboxylase activity; identical protein binding activity; and putrescine binding activity. Predicted to be involved in S-adenosylmethionine metabolic process; spermidine biosynthetic process; and spermine biosynthetic process. Predicted to act upstream of or within polyamine biosynthetic process. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; cranium; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human AMD1 (adenosylmethionine decarboxylase 1). PHENOTYPE: Homozygous null mice display embryonic lethality before somite formation and embryonic growth arrest. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
