| Primary Identifier | MGI:1261775 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 100504663 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable GTPase binding activity; phosphatidylinositol 3-kinase inhibitor activity; and protein-membrane adaptor activity. Involved in autophagy; cellular response to glucose starvation; and regulation of protein phosphorylation. Acts upstream of or within defense response to virus; innate immune response; and regulation of triglyceride metabolic process. Located in axoneme; mitochondria-associated endoplasmic reticulum membrane contact site; and phagocytic vesicle. Part of phosphatidylinositol 3-kinase complex, class III. Orthologous to human ATG14 (autophagy related 14). PHENOTYPE: Mice homozygous for a conditional allele following delivery of a Tat-cre exhibit increased mucin accumulation in colonic epithelial spheroids. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
