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Protein Coding Gene : Clec4a2 C-type lectin domain family 4, member a2

Primary Identifier  MGI:1349412 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  26888
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable calcium ion binding activity and mannose binding activity. Predicted to be involved in antifungal innate immune response. Predicted to act upstream of or within adaptive immune response and innate immune response. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. Orthologous to human CLEC4A (C-type lectin domain family 4 member A).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased IgG2a, IgG2b and IgG3 levels, increased B cell proliferation, enlarged lymph nodes and degeneration of seminiferous tubules. [provided by MGI curators]
  • synonyms:
  • C-type lectin domain family 4, member a2,
  • Clecsf6,
  • C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 6,
  • Dcir1,
  • DCIR,
  • dendritic cell immunoreceptor,
  • Clec4a2

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

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Disease

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