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Allele : Smad1<tm2Sor> SMAD family member 1; targeted mutation 2, Philippe Soriano
Primary Identifier  MGI:3045219 Allele Type  Targeted
Gene  Smad1 Transmission  Germline
Strain of Origin  129S4/SvJaeSor Is Recombinase  false
Is Wild Type  false
molecularNote  Homologous recombination incorporated serine to alanine substitutions in the MAPK-consensus phosphorylation sites (p.S187A, p.S195A, p.S206A, p.S214A) and two conserved phosphoserines in exon 3 (p.(S209_S210delinsAA)). Western blot analysis of MEF nuclear extracts demonstrated the mutant protein was expressed at similar levels as that of wild-type.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Smad1<L>,
  • Smad1<L>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele




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