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Protein Coding Gene : Herc6 hect domain and RLD 6
Primary Identifier  MGI:1914388 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  67138
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable cyclin binding activity and ubiquitin protein ligase activity. Acts upstream of or within hematopoietic progenitor cell differentiation and response to bacterium. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cytoplasm. Is expressed in liver. Orthologous to human HERC6 (HECT and RLD domain containing E3 ubiquitin protein ligase family member 6).
PHENOTYPE: Mice homozygous for a null allele exhibit enlarged seminal vesicles but do not show any abnormal responses to Sendai virus or vesicular stomatitis virus infection or to IFN stimulation. [provided by MGI curators]
  • synonyms:
  • EST AI451296,
  • 4930427L17Rik,
  • CEB1,
  • AI451296,
  • MGI:1889836,
  • 1700121D12Rik,
  • MGI:1921562,
  • Herc5,
  • hect domain and RLD 6,
  • MGI:1921870,
  • 2510038N07Rik,
  • hect domain and RLD 5,
  • Herc6,
  • RIKEN cDNA 4930427L17 gene,
  • RIKEN cDNA 2510038N07 gene,
  • RIKEN cDNA 1700121D12 gene
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