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Protein Coding Gene : Gmcl1 germ cell-less, spermatogenesis associated 1

Primary Identifier  MGI:1345156 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  23885
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Acts upstream of or within regulation of DNA-templated transcription. Located in nuclear envelope and nuclear matrix. Is expressed in several structures, including eye; genitourinary system; hemolymphoid system gland; liver; and lung. Orthologous to several human genes including GMCL1 (germ cell-less 1, spermatogenesis associated).
PHENOTYPE: Homozygotes for a targeted null mutation exhibit impaired nuclear membrane integrity in liver, endocrine pancreas, and testis. Mutant males show reduced fertility with decreased chromatin condensation and morphologically abnormal sperm. [provided by MGI curators]
  • synonyms:
  • germ cell-less homolog (Drosophila),
  • germ cell-less, spermatogenesis associated 1,
  • Gmcl1,
  • MGI:1919974,
  • mglc-1,
  • 2810049L19Rik,
  • RIKEN cDNA 2810049L19 gene,
  • Gcl,
  • Btbd13

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For