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Protein Domain : Pleckstrin homology domain, Mcp5-type

Primary Identifier  IPR024774 Type  Domain
Short Name  PH_dom-Mcp5-type
description  This pleckstrin homology domain is found in eukaryotic proteins, including Mcp5, a fungal protein that anchors dynein at the cell cortex during the horsetail phase (prophase I) of meiosis. During prophase I of fission yeast all the telomeres become bundled at the spindle pole body and subsequently the nucleus undergoes a dynamic oscillation, resulting in elongated nuclear morphology known as "horsetail"nucleus. The pleckstrin homology domain is necessary for the cortical localisation of the Mcp5 protein during meiosis [].

0 Child Features

1 Parent Features

0 Protein Domain Regions