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Publication : Genomic organization and 5'-flanking DNA sequence of the murine stomatin gene (Epb72).

First Author  Gallagher PG Year  1996
Journal  Genomics Volume  34
Issue  3 Pages  410-2
PubMed ID  8786142 Mgi Jnum  J:33859
Mgi Id  MGI:81352 Doi  10.1006/geno.1996.0304
Citation  Gallagher PG, et al. (1996) Genomic organization and 5'-flanking DNA sequence of the murine stomatin gene (Epb72). Genomics 34(3):410-2
abstractText  Stomatin is a poorly understood integral membrane protein that is absent from the erythrocyte membranes of many patients with hereditary stomatocytosis. This report describes the cloning of the murine stomatin chromosomal gene, determination of its genomic structure, and characterization of the 5'-flanking genomic DNA sequences. The stomatin gene is encoded by seven exons spread over approximately 25 kb of genomic DNA. There is no concordance between the exon structure of the stomatin gene and the locations of three domains predicted on the basis of protein structure. Inspection of the 5'-flanking DNA sequences reveals features of a TATA-less housekeeping gene promoter and consensus sequences for a number of potential DNA-binding proteins.
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