Primary Identifier | MGI:894835 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 19647 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable protein kinase binding activity and ubiquitin protein ligase activity. Involved in ubiquitin-dependent protein catabolic process. Acts upstream of or within embryonic organ development; in utero embryonic development; and somite development. Predicted to be located in nuclear speck. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. Predicted to colocalize with centrosome. Is expressed in left lung and right lung. Orthologous to human RBBP6 (RB binding protein 6, ubiquitin ligase). PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality, reduced size, growth retardation and increased apoptosis. [provided by MGI curators] |