| Primary Identifier | MGI:1921452 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 74202 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable filamin binding activity. Predicted to be involved in cell-cell adhesion and regulation of integrin activation. Predicted to act upstream of or within cell adhesion and regulation of cell shape. Predicted to be located in several cellular components, including cell junction; cell periphery; and fibrillar center. Predicted to be active in focal adhesion and stress fiber. Is expressed in several structures, including central nervous system; early conceptus; reproductive system; sensory organ; and urinary system. Orthologous to human FBLIM1 (filamin binding LIM protein 1). PHENOTYPE: Mice homozygous for one knock-out allele exhibit severe osteopenia with decreased osteoblasts and increased osteoclasts. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
