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Protein Coding Gene : Fbxl3 F-box and leucine-rich repeat protein 3
Primary Identifier  MGI:1354702 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  50789
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Contributes to ubiquitin-protein transferase activity. Involved in several processes, including SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; entrainment of circadian clock by photoperiod; and protein destabilization. Located in cytosol and nucleus. Is expressed in embryo; extraembryonic component; inner cell mass; and trophectoderm. Orthologous to human FBXL3 (F-box and leucine rich repeat protein 3).
PHENOTYPE: Both heterozygous and homozygous mutant mice display a longer free running period than that of wild-type mice. [provided by MGI curators]
  • synonyms:
  • Ovtm,
  • overtime,
  • Fbxl3a,
  • F-box and leucine-rich repeat protein 3,
  • play 68,
  • F-box and leucine-rich repeat protein 3a,
  • expressed sequence AU041772,
  • Fbxl3,
  • MGI:2661838,
  • expressed sequence AW212966,
  • Play68,
  • Fbl3a,
  • MGI:3606318,
  • MGI:2145805,
  • AW212966,
  • MGI:2145757,
  • AU041772
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1 Involved In Mutations

Trail: ProteinCodingGene

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

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Function

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7 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

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