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Protein Coding Gene : Use1 unconventional SNARE in the ER 1 homolog (S. cerevisiae)
Primary Identifier  MGI:1914273 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  67023
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable SNAP receptor activity. Acts upstream of or within endoplasmic reticulum tubular network organization and regulation of ER to Golgi vesicle-mediated transport. Predicted to be located in COPI-coated vesicle. Predicted to be part of SNARE complex. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including early conceptus; embryo ectoderm; embryo mesoderm; optic vesicle; and primitive streak. Orthologous to human USE1 (unconventional SNARE in the ER 1).
PHENOTYPE: Homozygous inactivation of this gene results in complete embryonic lethality prior to E8.5. [provided by MGI curators]
  • synonyms:
  • 5730403H22Rik,
  • Q-SNARE,
  • Use1,
  • RIKEN cDNA 5730403H22 gene,
  • RIKEN cDNA 2010315L10 gene,
  • AV002165,
  • unconventional SNARE in the ER 1 homolog (S. cerevisiae),
  • MGI:1924098,
  • D12,
  • mED2,
  • expressed sequence AV002165,
  • 2010315L10Rik,
  • MGI:2142729
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1 Involved In Mutations

Trail: ProteinCodingGene

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

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Interactions

5 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

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Disease

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