First Author | Broad TE | Year | 1995 |
Journal | Mamm Genome | Volume | 6 |
Issue | 3 | Pages | 202-5 |
PubMed ID | 7749229 | Mgi Jnum | J:24437 |
Mgi Id | MGI:72135 | Doi | 10.1007/BF00293014 |
Citation | Broad TE, et al. (1995) Four human chromosome 3q and four human chromosome 21 loci map onto sheep chromosome 1q. Mamm Genome 6(3):202-5 |
abstractText | Eight new loci have been assigned to sheep Chromosome (Chr) 1q by use of a chromosomally characterized minipanel of sheep x hamster cell hybrids. Four loci, which have been mapped to the distal region of human Chr 3q, are ceruloplasmin (CP), sucrase isomaltase (SI), glucose transporter 2 (GLUT2), and ectopic viral integration site 1 (EVI1). The other four loci, on human Chr 21, include interferon alpha receptor (IFNAR); interferon inducible protein p78, murine (MX1); collagen type VI, alpha 1 (COL6A1); and S100 protein, beta polypeptide (S100B). All of these loci, except GLUT2 and MX1, have been mapped onto bovine Chr 1 or are syntenic with loci on this chromosome. The in situ localization of transferrin (TF) to sheep Chr 1q42-q45 confirms our previous assignment of this locus and independently anchors the eight new syntenic loci to sheep Chr 1q. |