| First Author | Ramot A | Year | 2017 |
| Journal | Nat Neurosci | Volume | 20 |
| Issue | 3 | Pages | 385-388 |
| PubMed ID | 28135239 | Mgi Jnum | J:244412 |
| Mgi Id | MGI:5913191 | Doi | 10.1038/nn.4491 |
| Citation | Ramot A, et al. (2017) Hypothalamic CRFR1 is essential for HPA axis regulation following chronic stress. Nat Neurosci 20(3):385-388 |
| abstractText | The hypothalamic-pituitary-adrenal axis is a pivotal component of an organism's response to stressful challenges, and dysfunction of this neuroendocrine axis is associated with a variety of physiological and psychological pathologies. We found that corticotropin-releasing factor type 1 receptor within the paraventricular nucleus of the hypothalamus is an important central component of hypothalamic-pituitary-adrenal axis regulation that prepares the organism for successive exposure to stressful stimuli. |
