| Primary Identifier | MGI:106673 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 11550 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables alpha1-adrenergic receptor activity. Involved in neuron-glial cell signaling and regulation of blood pressure. Acts upstream of or within negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure and norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in brain; diencephalon; and forebrain. Orthologous to human ADRA1D (adrenoceptor alpha 1D). PHENOTYPE: Mice homozygous for disruptions in this gene display hypotension or reduced rearing behavior in a novel environment, decreased wheel-running activity during the night, and reduced hyperlocomotion after amphetamine administration. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
