| Primary Identifier | MGI:103287 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 22184 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable identical protein binding activity and pre-mRNA 3'-splice site binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing and mRNA processing. Located in nucleolus. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system gland; intestine; and sensory organ. Human ortholog(s) of this gene implicated in acute myeloid leukemia and myelodysplastic syndrome. Orthologous to several human genes including ZRSR2 (zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2). PHENOTYPE: Mice inheriting a null allele maternally and a paternal null allele for Zrsr1 fail to develop beyond the 2 cell stage, with very few reaching morula stage and none implanting. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
