First Author | Tan SH | Year | 2015 |
Journal | Cancer Cell | Volume | 28 |
Issue | 6 | Pages | 683-685 |
PubMed ID | 26678334 | Mgi Jnum | J:227327 |
Mgi Id | MGI:5700243 | Doi | 10.1016/j.ccell.2015.11.004 |
Citation | Tan SH, et al. (2015) Stemming Colorectal Cancer Growth and Metastasis: HOXA5 Forces Cancer Stem Cells to Differentiate. Cancer Cell 28(6):683-5 |
abstractText | Wnt signaling drives colorectal cancer stem cells, but effective therapeutics targeting these cells and their signaling pathways are lacking. In this issue of Cancer Cell, Ordonez-Moran and colleagues describe a promising therapeutic intervention for colorectal cancers that selectively induces cancer stem cell differentiation through HOXA5 expression and Wnt signaling inhibition. |