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Protein Coding Gene : Chn1 chimerin 1

Primary Identifier  MGI:1915674 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  108699
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables ephrin receptor binding activity. Involved in ephrin receptor signaling pathway; motor neuron axon guidance; and regulation of axonogenesis. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and immune system. Used to study Duane retraction syndrome. Human ortholog(s) of this gene implicated in Duane retraction syndrome. Orthologous to human CHN1 (chimerin 1).
PHENOTYPE: Mice homologous for a null allele exhibit transient postnatal size reduction, abnormal gait and abnormal innervation of the spinal cord. [provided by MGI curators]
  • synonyms:
  • alpha2 chimaerin,
  • RIKEN cDNA 0610007I19 gene,
  • MGI:1915574,
  • 1700112L09Rik,
  • 2900046J01Rik,
  • MGI:1925592,
  • alpha1 chimaerin,
  • RIKEN cDNA 2900046J01 gene,
  • chimerin 1,
  • Chn1,
  • 0610007I19Rik,
  • MGI:1923974,
  • 0710001E19Rik,
  • RIKEN cDNA 1700112L09 gene,
  • AI413815,
  • RIKEN cDNA 0710001E19 gene,
  • ARHGAP2,
  • expressed sequence AI413815,
  • MGI:2138925

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

7 Involved In Mutations

0 Strain

0 Transcripts

2 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For