Primary Identifier | MGI:7290061 | Allele Type | Endonuclease-mediated |
Attribute String | Endonuclease, Inserted expressed sequence, Reporter | Gene | Gt(ROSA)26Sor |
Inheritance Mode | Not Specified | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
molecularNote | These mice harbor a CAG-LSL-3xKRAB-dCas9-IRES-EGFP-WPRE-pA conditional expression cassette in mouse Rosa26 loci via homologous recombination. This strain can be used in CRISPR mediated target gene transcriptional inhibition (CRISPRi). The loxp-stop-loxp cassette was deleted. |