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Protein Domain : Ubinuclein-2

Primary Identifier  IPR026943 Type  Family
Short Name  Ubinuclein-2
description  This entry represents ubinuclein-2 (UBN2). It contains a conserved HIRA-binding domain, which directly interacts with the N-terminal WD repeats of HIRA []. UBN2 and UBN1 are believed to be the orthologs of Hpc2p, a subunit of the HIR complex (a nucleosome assembly complex involved in regulation of histone gene transcription) in budding yeast []. It is phosphorylated upon DNA damage, probably by ATM or ATR [].

0 Child Features

0 Parent Features

3 Protein Domain Regions